Mesotherapy, Microneedling and SMARTMeso: Which Should You Choose for Your Salon or Clinic?

Mesotherapy, Microneedling and SMARTMeso: Which Should You Choose for Your Salon or Clinic?

A woman is getting a facial treatment at a beauty salon.

The eternal quest for perfect skin has led to treatments such as mesotherapy and microneedling becoming commonplace in salons and clinics. However, with this comes rising confusion over the different types of treatments, the side effects and downtime. 


With so many options on the market, it’s worth doing your research. This blog breaks down the different options - including mesotherapy, microneedling and
SMARTMeso.


Skin Needling Treatments: Traditional Mesotherapy and Microneedling

Mesotherapy and microneedling are two of the most commonly offered skin treatments, both involving needling techniques. However, they do differ in terms of needle length, application, depth of penetration and speed of delivery.


Mesotherapy is a French treatment originally developed to inject medicine into subcutaneous fat. Now widely used for skin rejuvenation, it involves micro injections of vitamins, enzymes, antioxidants and plant extracts to nourish, repair and rejuvenate skin. With mesotherapy, patients can be assured that only a natural potent of liquid is penetrating the skin to rejuvenate it.


Microneedling, on the other hand, is a cosmetic procedure that’s used to treat skin concerns via collagen production. The minimally invasive derma roller procedure uses small needles to prick the skin.


The Use of Needles for Treatment

Both treatments are effective for reducing the appearance of fine lines and wrinkles, however, they do rely on needles for treatment, making these treatment types unsuitable for all clients.


Mesotherapy is carried out with a single needle entering the skin, whereas microneedling requires multiple needles at once through a roller or pen device. This can be uncomfortable, the pain for microneedling often being significant enough for topical anaesthetic to be applied prior to treatment. This also indicates the amount of downtime clients can expect, causing mild-to-moderate redness, swelling, or skin sensitivity to touch for up to three days.


While mesotherapy does not require anaesthetic, clients may experience a mild tingling sensation on the skin for up to 48 hours.


Transdermal Mesotherapy: SMARTMeso

Although needle treatments can be found on treatment menus in salons up and down the country, there is a growing demand for a transdermal solution. This is where SMARTMeso comes in, providing an effective, innovative, needle-free mesotherapy for skin and hair. 


Combining two unique technologies, SMARTMeso delivers products deep into the skin for efficient treatment results, targeting fine lines and wrinkles, whilst redefining facial contours. The unique transdermal serum delivery results in 85% improved absorption to produce outstanding results, an attractive feature for clients who desire progressive long-term skin health without the need for needles.


SMARTMeso allows clinics and salons to capture the large market share of clients who desire improved skin and hair health without the downtime or pain associated with regular mesotherapy or microneedling. SMARTMeso can be used as either a stand-alone treatment, layered into other treatments, or even used as a delivery system for other products.⁣



Try SMARTMeso for yourself, and discover why salons across the UK are moving away from traditional mesotherapy and microneedling, and choosing SMARTMeso. 

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By Dee Malan September 4, 2026
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